In any commercial setting—whether it is a hotel, office, school, airplane or even a hospital—public restrooms represent one of the biggest infection prevention challenges and are areas with the greatest potential for germ cross-contamination. Due to their function and constant use, everything from urine and fecal matter to other bodily fluids and dirt contribute to restroom cleaning challenges daily. Not to mention, every time a toilet is flushed, it releases a plume of aerosolized droplets that can carry bacteria to other restroom surfaces like floors, walls, and handles,1 heightening cross-contamination concerns.